US PTO 8,809,515 "515" Provides Opportunity to Design, Optimize and Target Dicerna's DsiRNAs in Drug Development
The newly issued claims provide broad protection for the therapeutic use of DsiRNA oligonucleotides, a technology at the core of Dicerna's current product pipeline development programs. In their breadth, the issued claims clearly establish the dicer substrate technology as a distinct platform approach to harnessing the RNAi phenomenon in the development of human therapeutic products for multiple indications. The collection of recently issued claims cover composition and method of use type claims that allow an expansive approach to the use of DsiRNAs with minimal restriction on the molecular structure of DsiRNAs; thereby, maximizing the design flexibility in preparing therapeutic molecules.
"As we move into clinical development of our product candidates, the
issuance of these new patents adds significantly to our intellectual
property estate. These patents also strengthen the original
"This has been a productive period in the prosecution of these cases.
These patents broadly support our activities and those of our partners,"
About Dicerna Pharmaceuticals, Inc.
Dicerna is a biopharmaceutical company focused on the discovery and development of innovative treatments for rare, inherited diseases involving the liver and for cancers that are genetically defined. The Company is using its proprietary RNA interference (RNAi) technology platform to build a broad pipeline in these therapeutic areas. In both rare diseases and oncology, Dicerna is pursuing targets that have historically been difficult to inhibit using conventional approaches, but where connections between targets and diseases are well understood and documented. The Company intends to discover, develop and commercialize novel therapeutics either on its own or in collaboration with pharmaceutical partners. For more information, please visit www.dicerna.com.
Cautionary Note on Forward-Looking Statements
This press release includes forward-looking statements, including statements regarding Dicerna's clinical development. Such forward-looking statements are subject to risks and uncertainties, including financial, scientific, and regulatory risks regarding clinical development that could cause actual results to differ materially from those expressed or implied in such statements. Applicable risks and uncertainties include those identified under the heading "Risk Factors" included in the Form 10-Q filed August 7, 2014, and in other filings that Dicerna may make with the SEC in the future. The forward-looking statements contained in this press release reflect Dicerna's current views with respect to future events, and Dicerna does not undertake and specifically disclaims any obligation to update any forward-looking statements.
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