Investors & Media
Doug M. Fambrough, III, Ph.D., has served as a member of our board of directors since April 2007 and as our president and chief executive officer since May 2010. From 2000 to May 2010, Dr. Fambrough held various positions at Oxford Bioscience Partners, a life science venture capital firm, most recently as a general partner. During his years at Oxford Bioscience Partners, he specialized in financing innovative life science technology companies, including the Company, Sirna Therapeutics, Inc. (acquired by Merck & Co., Inc.), Solexa, Inc. (acquired by Illumina, Inc.), and Xencor, Inc. (NASDAQ: XNCR), and served as a director of each of these companies. Dr. Fambrough has also served as a Trustee of Boston Biomedical Research Institute, a not-for-profit organization. Before joining Oxford Bioscience Partners, he was a genomic scientist at the Whitehead/MIT Center for Genome Research (now known as the Broad Institute).
Dr. Fambrough graduated from Cornell University and obtained his Ph.D. in Genetics at the University of California, Berkeley.
Bob D. Brown, Ph.D. initially served as our senior vice president of research beginning in May 2008 and has served as our chief scientific officer since January 2012. From March 2003 to March 2008, Dr. Brown held various positions at Genta Incorporated, most recently as its vice president of research and technology. Previously, he was a co-founder and vice president of research and development of Oasis Biosciences Inc., which was acquired by Gen-Probe Incorporated. Dr. Brown is an inventor or co-inventor on 16 issued patents and dozens of patent applications covering oligonucleotide and conventional small molecule therapeutic agents, diagnostic tool and oligonucleotide and small molecule drug delivery technologies.
Dr. Brown holds a Ph.D. in molecular biology from the University of California, Berkeley, and a B.S. in chemistry and biology from the University of Washington, Seattle.
Jack Green joined Dicerna as Chief Financial Officer in April 2016. Prior to Dicerna, he was Chief Financial Officer of Verastem, Inc. (VSTM). Previously, Jack served for over 15 years as Chief Financial Officer of GTC Biotherapeutics, Inc. (GTCB; formerly Genzyme Transgenics Corporation), which was spun out from Genzyme Corporation as a stand-alone public company.
Jack is a Certified Public Accountant (CPA) with over 30 years of financial management experience, including 20 within the biotechnology industry. He received a Master’s degree in business administration from Boston University Graduate School of Management and a Bachelor’s degree from the College of the Holy Cross majoring in Economics and Accounting.
Jennifer Lockridge, Ph.D., is VP of Program Development at Dicerna Pharmaceuticals and has twenty years of experience in the development of oligonucleotide therapeutics. She currently oversees development programs at Dicerna and supporting nonclinical activities. Prior to joining Dicerna, Dr. Lockridge spent nine years consulting with multiple biotech and large pharmaceutical companies to provide direction and support for early development stage oligonucleotide programs as well as pharmacology and pharmacokinetics expertise. From 1996 to 2007, she was employed at Sirna Therapeutics, Inc. (formerly Ribozyme Pharmaceuticals, Inc.). As Director of Project Management at Sirna, she managed and was involved with all aspects of siRNA and ribozyme development programs. Dr. Lockridge received her Ph.D. in pharmacology at the Oregon Health Sciences University, Portland, Oregon and pursued postdoctoral training at the FDA’s National Center for Toxicological Research, Jefferson, Arkansas.
David Miller has successfully combined leadership roles in both business and research capacities. He has been a member of five early stage biotech companies, each of which has successfully transitioned to a public company. Currently, he is Senior Vice President, Corporate Operations at Dicerna Pharmaceuticals, Cambridge, MA, where he has been the past eight years. At Dicerna, he has also occupied the roles of Vice President of Research Operations and of Business Development. Dr. Miller was Senior Director, Business Development at Synta Pharmaceuticals, where he had partnering responsibility for their oncology portfolio and played a lead role in a pharma partnership, valued at over $1 billion. Prior to this, he was Director, Business Development at Altus Biologics where his responsibilities included developing their drug delivery business and the partnering of several biological products. Dr. Miller was a founder and the head of research for EcoScience Corporation, an agricultural biotechnology company. He began his career at Genetics Institute. Dr. Miller is the inventor on six issued United States patent. He is a board member of EcoPesticides International, a New Mexico company, and on several public boards in his hometown of Winchester, MA.
Dr. Miller holds a Ph.D. in molecular biology and biochemistry from Harvard University and a B.S. in biochemistry and biophysics from the University of California, Davis.
Ralf Rosskamp, M.D., joined Dicerna as chief medical officer in June 2017. Dr. Rosskamp brings to Dicerna more than 20 years of research and development (R&D) experience spanning the entire drug development cycle, from pre-clinical through product commercialization. He will be responsible for leading the Company’s clinical development, medical affairs and regulatory functions.
Prior to joining Dicerna, Dr. Rosskamp was chief medical officer at Summit Therapeutics. In this role, Dr. Rosskamp was responsible for directing and overseeing all clinical development and medical activities for Summit’s clinical candidates in development for the rare genetic disease Duchenne muscular dystrophy and the infectious disease caused by Clostridium difficile bacteria. Prior to Summit, Dr. Rosskamp held executive-level positions in clinical research and drug development at NPS Pharmaceuticals (acquired by Shire), Ikaria, Kos Pharmaceuticals (acquired by Abbott Laboratories), Aventis Pharmaceuticals (formerly Hoechst Marrion Roussel), and Hoechst AG.
Dr. Rosskamp has been responsible for numerous investigational new drug applications, the design and execution of clinical development programs, and new drug applications across multiple therapeutic areas including diabetes, cardiovascular, respiratory and orphan drugs. Approved products for which Dr. Rosskamp was involved include Amaryl®, Lantus®, Apidra®, Simcor® and Natpara® for the treatment of a rare endocrine disease called hypoparathyroidism.
Dr. Rosskamp is a member of the Board of Directors of Bioblast Pharma in Tel Aviv, Israel. He has authored more than 20 peer-reviewed publications and published more than 50 scientific abstracts. Dr. Rosskamp is a pediatric endocrinologist with more than 15 years of experience in clinical medicine. He received his M.D. from the University of Bonn, Germany.
James B. Weissman has served as our chief business officer since January 2012. From January 2006 to January 2012, Mr. Weissman was senior director and then vice president, business development of MannKind Corporation (NASDAQ: MNKD), where he was responsible for leading the company’s activities related to licensing, new products and strategic planning. Prior to MannKind, Mr. Weissman held leadership positions in both business development and marketing at Pfizer Pharmaceuticals, Inc. in Tokyo, most recently as senior director of marketing, responsible for the sales, profit and strategic targets for the company’s specialty products, in a variety of therapeutic areas.
Mr. Weissman holds a B.S. from Bates College in Maine.
Bart Wise joined Dicerna as senior vice president, intellectual property in October 2015. He has practiced for more than 15 years in the life sciences industry, with extensive experience in intellectual property (IP) strategy and patent portfolio management.
Prior to Dicerna, Bart had his own law practice, where he assisted clients with licensing, agreements, patent matters, and business issues. Bart also held positions in intellectual property at Roche Molecular Systems, Geron, and most recently, as vice president of Intellectual Property at Five Prime Therapeutics. In that position, he was a member of Five Prime’s leadership team and was responsible for all the company’s intellectual property. Bart began his legal career as an associate at the international IP law firm Finnegan, Henderson, where he worked in litigations, interferences, and patent drafting and prosecution.
Bart holds a B.S. degree in Chemistry from the University of Kansas, a Ph.D. degree in Biology from Carnegie Mellon University, and a J.D. degree from the University of California, Berkeley School of Law. He was also a Howard Hughes.